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Updated: Sep 20, 2025
07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
536
Interventional Therapies for Acute Pulmonary Embolism.
Asishana A Osho1, David M Dudzinski2
1Division of Cardiac Surgery, Massachusetts General Hospital, Cox 6, 55 Fruit Street, Boston, MA 02114, USA.
The Surgical Clinics of North America
|June 7, 2022
Summary
Pulmonary embolism (PE) management requires early anticoagulation. For high-risk cases, consider thrombolysis or interventions, with pulmonary embolism response teams (PERT) aiding multidisciplinary care.
Area of Science:
- Cardiology
- Pulmonary Medicine
- Interventional Radiology
Background:
- Pulmonary embolism (PE) is a leading cause of cardiovascular death.
- Current guidelines have low-strength recommendations for interventional therapies due to data gaps.
- Effective PE management strategies are crucial.
Purpose of the Study:
- To review current management strategies for pulmonary embolism.
- To highlight the role of interventional therapies and the need for outcome data.
- To emphasize the utility of pulmonary embolism response teams (PERT).
Main Methods:
- Review of existing literature and clinical guidelines on PE management.
- Analysis of risk stratification and therapeutic options for acute PE.
- Discussion of systemic thrombolysis, interventional procedures, and supportive care.
Main Results:
- Anticoagulation is a cornerstone of early PE management.
- Systemic thrombolysis is recommended for high-risk PE after bleeding risk assessment.
- Interventional therapies (catheter-directed lysis/embolectomy, surgery, mechanical support) are options for specific patient groups.
Conclusions:
- Evidence gaps in interventional therapy outcomes necessitate careful patient selection.
- Pulmonary embolism response teams (PERT) can facilitate multidisciplinary evaluation and treatment.
- Further research is needed to strengthen recommendations for advanced PE interventions.
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