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Renal Cell Carcinoma Metastasis to the Left Atrium
Aizaz Ali1, Saeedullah Shah1, Muhammad Furrukh2
1Department of Cardiology, Shifa International Hospital, Islamabad, Pakistan.
Abstract:
Only 13 cases of renal cell carcinoma metastasis to the left atrium of the heart have been described. We report the case of a man in his 50s who had undergone radical nephrectomy for renal cell carcinoma in 2006 and presented with amnesia at our neurology department in 2020. Magnetic resonance images of the brain showed metastatic lesions; subsequent computed tomograms of the chest, abdomen, and pelvis revealed a mass in the left atrium and multiple metastases in the lung, pleura, and pancreas. Our cardiologists advised against surgical removal of the left atrial mass because of a poor prognosis, so radiation therapy and immunotherapy were initiated instead.
Insights
This case report details a rare instance of renal cell carcinoma (RCC) spreading to the heart's left atrium. Treatment involved radiation and immunotherapy due to the advanced stage of this rare cancer metastasis.
Area of Science:
- Oncology
- Cardiology
- Radiology
Background:
- Renal cell carcinoma (RCC) is a primary kidney cancer.
- Metastasis to the heart is a rare but serious complication of advanced RCC.
Observation:
- A man in his 50s with a history of radical nephrectomy for RCC presented with amnesia.
- Brain MRI revealed metastatic lesions, and CT scans showed a left atrial mass with lung, pleural, and pancreatic metastases.
Findings:
- This case represents one of only 13 documented instances of RCC metastasis to the left atrium.
- The patient had widespread metastatic disease involving the brain, lungs, pleura, pancreas, and left atrium.
Implications:
- The prognosis for left atrial metastasis from RCC is generally poor.
- Treatment strategies may include radiation therapy and immunotherapy when surgical intervention is not feasible.
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