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Quantitative Analysis of Cell Edge Dynamics during Cell Spreading
Published on: May 22, 2021
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Hidden dependence of spreading vulnerability on topological complexity.
Mark M Dekker1, Raoul D Schram2, Jiamin Ou3
1Department of Information and Computing Sciences, Utrecht University, Princetonplein 5, 3584 CC Utrecht, The Netherlands.
Physical Review. E
|June 16, 2022
Summary
We introduce the entropy of temporal entanglement to quantify spreading vulnerability in complex systems. This new measure accurately predicts how easily phenomena spread across dynamic temporal networks, regardless of system specifics.
Area of Science:
- Complex Systems Science
- Network Science
- Dynamical Processes
Background:
- Spreading phenomena in complex systems occur on dynamic temporal networks.
- Quantifying a system's susceptibility to spreading (spreading vulnerability) from network topology is challenging.
- Existing methods struggle to compare spreading vulnerability across diverse complex systems.
Purpose of the Study:
- To develop a novel, parameter-free metric for measuring the topological complexity of temporal networks.
- To establish a quantitative link between temporal network topology and spreading vulnerability.
- To enable cross-system comparisons of spreading potential.
Main Methods:
- Developed the "entropy of temporal entanglement" metric.
- Utilized data from diverse real-world complex systems.
- Simulated three types of stochastic dynamical spreading processes on temporal networks.
Main Results:
- The entropy of temporal entanglement quantifies topological complexity in temporal networks.
- This metric allows for parameter-free comparisons across different complex systems.
- The entropy of temporal entanglement accurately predicts spreading vulnerability irrespective of the spreading process dynamics.
Conclusions:
- The entropy of temporal entanglement is a robust measure of spreading vulnerability in temporal networks.
- This entropic measure offers a unified approach to understanding spreading dynamics across various systems.
- Potential applications span natural, social, biological, and engineered domains.
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