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Right Heart Failure in Mice Upon Pressure Overload Is Promoted by Mitochondrial Oxidative Stress

Marion Müller1,2, Cornelius Bischof1,2, Torben Kapries1,2

  • 1Clinic for General and Interventional Cardiology/Angiology, Herz- und Diabeteszentrum NRW, University Hospital of the Ruhr-Universität Bochum, Bad Oeynhausen, Germany.

JACC. Basic to Translational Science
|August 12, 2022
PubMed

Keywords:
6J, C57BL/6J6N, C57BL/6NNNT, nicotinamide nucleotide transhydrogenasePAB, pulmonary artery bandingRHF, right heart failureRVD, right ventricular dysfunctionRVH, right ventricular hypertrophyTAPSE, tricuspid annular plane systolic excursioniRVF, severely impaired right ventricular functionnRVF, normal right ventricular functionoxidative stresspressure overloadpulmonary artery bandingreactive oxygen speciesright heart failure

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