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Updated: Sep 1, 2025

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry
09:14

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry

Published on: July 20, 2016

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Fast Cysteine Bioconjugation Chemistry.

Fa-Jie Chen1, Jianmin Gao1

  • 1Department of Chemistry, Boston College, Merkert Chemistry Center, 2609 Beacon Street, Chestnut Hill, MA 02467, USA.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|August 15, 2022
PubMed
Summary

Fast cysteine bioconjugation enables precise protein modification for research applications. New reagents offer high efficiency, minimizing side reactions and simplifying purification for antibody-drug conjugates and cell imaging.

Keywords:
N-terminal cysteinecysteine bioconjugationfast kineticsprotein modificationreaction rate constant

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