[Changes in the phospholipid composition of liver mitochondrial membranes in rats treated with ethanol]

Phospholipid composition was studied in liver mitochondrial membranes of rats consuming ethanol for a long time. A new phospholipid phosphatidyl ethanol was found in the membranes, which appears to be formed due to the action of endogenous phospholipase D. The phospholipase D activity was measured in mitochondria using direct evaluation. Administration of ethanol led to alteration in the ratio of mitochondrial phospholipids.