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Updated: Aug 30, 2025

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A Multi-detection Assay for Malaria Transmitting Mosquitoes
Published on: February 28, 2015
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Malaria Surveillance - United States, 2018
Kimberly E Mace1, Naomi W Lucchi1, Kathrine R Tan1
1Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, CDC.
Summary
Malaria cases in the U.S. decreased in 2018, with most imported from Africa. Poor adherence to malaria chemoprophylaxis among travelers remains a significant concern for prevention efforts.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- Malaria is a significant public health concern, primarily transmitted by Anopheles mosquitoes.
- While most U.S. cases are imported due to travel, local transmission can occur.
- Malaria surveillance is crucial for understanding occurrence, guiding prevention, and controlling outbreaks.
Purpose of the Study:
- To summarize confirmed malaria cases in the U.S. in 2018 and analyze trends.
- To identify the origins, species, and risk factors associated with malaria cases.
- To assess antimalarial drug resistance markers and evaluate prevention strategies.
Main Methods:
- Data collected through National Malaria Surveillance System (NMSS) and National Notifiable Diseases Surveillance System (NNDSS).
- Includes CDC clinical consultations and reference laboratory reports.
- Analysis of confirmed malaria cases, including species, origin, and drug resistance markers.
Main Results:
- 1,823 confirmed malaria cases in 2018, a 15.6% decrease from 2017.
- 85% of cases were imported, predominantly from Africa (West Africa).
- Plasmodium falciparum was the most common species; poor chemoprophylaxis adherence was noted (95%).
Conclusions:
- Imported malaria cases reflect global travel patterns, with a notable decrease in 2018.
- Improving traveler adherence to chemoprophylaxis is essential for reducing imported cases.
- Continued surveillance and molecular monitoring for drug resistance are vital for malaria control.
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