Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

702
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
702
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

628
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
628
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

527
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
527
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

6.3K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute Paracentral Scotoma Following Cosmetic Penile Filler Injection.

Retinal cases & brief reports·2026
Same author

Clinical Characteristics and Outcomes of Hemorrhagic Choroidal Detachments From 2003-2020: A Single Center Experience.

Ophthalmic surgery, lasers & imaging retina·2026
Same author

The evolving role of artificial intelligence in ophthalmology: basic science, translation, and clinical integration.

Current opinion in ophthalmology·2026
Same author

Surgical technology update for ophthalmic surgery: heads-up display, artificial intelligence, instrumentation, and robotics.

Current opinion in ophthalmology·2026
Same author

Spectrum of Colopathy and Severe Polyposis Associated With Pentosan Polysulfate Sodium Maculopathy: A Retrospective Case Series.

American journal of ophthalmology·2026
Same author

Stromal Keratitis in the Zoster Eye Disease Study: Lessons Learned.

American journal of ophthalmology·2026
Same journal

Posterior Segment Pressurization With Intravitreal Balanced Salt Solution to Stabilize Anterior Chamber Gas During Endothelial Keratoplasty.

Cornea·2026
Same journal

Central Corneal Thickness Six Postoperative Months After DMEK or Triple-DMEK.

Cornea·2026
Same journal

Rebubbling and Graft Detachment in Pre-Descemet Endothelial Keratoplasty: A Prospective Study.

Cornea·2026
Same journal

Letter Regarding: ESCALÓN: A Prospective Randomized Trial of Corneal Endothelial Cell Therapy in Subjects With Corneal Edema.

Cornea·2026
Same journal

Osimertinib-Associated Benign Ocular Hyperpigmentation: A Case Report.

Cornea·2026
Same journal

Outcomes of Descemet Stripping Endothelial Keratoplasty in Eyes With Anterior Chamber Intraocular Lenses.

Cornea·2026
See all related articles

Related Experiment Video

Updated: Aug 28, 2025

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

1.4K

Oleander-Associated Keratitis and Uveitis.

Prashant D Tailor1, Marybeth K Farazdaghi, Sanjay V Patel

  • 1Department of Ophthalmology, Mayo Clinic, Rochester, MN.

Cornea
|September 15, 2022
PubMed
Summary
This summary is machine-generated.

Oleander plant exposure can cause severe eye inflammation, including keratitis, corneal edema, and anterior uveitis. Aggressive steroid treatment is often necessary for full recovery.

More Related Videos

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
04:00

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings

Published on: August 2, 2024

2.2K
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.5K

Related Experiment Videos

Last Updated: Aug 28, 2025

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

1.4K
Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
04:00

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings

Published on: August 2, 2024

2.2K
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.5K

Area of Science:

  • Ophthalmology
  • Toxicology

Background:

  • Oleander (Nerium oleander) is a poisonous plant with known systemic toxicity.
  • Ophthalmic side effects of oleander exposure are not well-documented in medical literature.

Observation:

  • A case report details a 58-year-old woman experiencing a corneal epithelial defect after direct eye contact with an oleander leaf.
  • Initial treatment with topical antibiotics was insufficient, leading to severe corneal edema and anterior uveitis.

Findings:

  • Oleander-associated ocular inflammation required aggressive immunomodulatory therapy, including oral and topical corticosteroids (prednisone, difluprednate) and cycloplegics (cyclopentolate).
  • The patient achieved significant improvement in visual acuity, anterior uveitis, and corneal edema with this aggressive treatment regimen.

Implications:

  • Ophthalmologists should consider oleander exposure in patients presenting with severe keratitis, corneal edema, and anterior uveitis.
  • Prompt and aggressive treatment with corticosteroids may be crucial to prevent persistent ocular sequelae following oleander exposure.