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Frailty and benign prostatic hyperplasia: The thrilling underlying impact.
Themistoklis Ch Bellos1, Lazaros I Tzelves2, Ioannis S Manolitsis3
12nd Department of Urology, Sismanoglio General Hospital of Athens, Athens. bellos.themistoklis@gmail.com.
Frailty negatively impacts outcomes for men with benign prostatic hyperplasia (BPH), increasing lower urinary tract symptoms (LUTS) and surgical risks. Prostatic stents may be ideal for frail patients.
Area of Science:
- Gerontology
- Urology
- Geriatric Medicine
Background:
- Global population aging trend highlights increased prevalence of age-related conditions.
- Benign prostatic hyperplasia (BPH) affects a significant percentage of aging men, causing lower urinary tract symptoms (LUTS).
- Older and frailer individuals are disproportionately affected by LUTS associated with prostate enlargement.
Purpose of the Study:
- To investigate the relationship between frailty syndrome and benign prostatic hyperplasia (BPH).
- To review the impact of frailty on BPH patient prognosis and treatment outcomes.
Main Methods:
- A non-systematic literature review of MEDLINE/PubMed was performed.
- Search terms included "frailty and benign prostatic hyperplasia" and "low muscle mass and benign prostatic hyperplasia".
- Literature search covered the period from 1990 to March 2022.
Main Results:
- Frailty is linked to a worse prognosis in BPH patients, with higher incidence of LUTS.
- Frailty predicts surgical failure and increased mortality after invasive BPH procedures.
- Prostatic stent placement emerges as a potentially suitable intervention for frail individuals with BPH.
Conclusions:
- Benign prostatic hyperplasia (BPH) is strongly associated with frailty and advanced age.
- Understanding this link is crucial for managing BPH in an aging population.
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