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Published on: March 29, 2018
Adenoid Ameloblastoma Versus Dentinogenic Ghost Cell Tumor
Victor Coutinho Bastos1, Carolina Cavaliéri Gomes1, Ricardo Santiago Gomez2
1Department of Pathology, Biological Science Institute (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Background:
A recent systematic review published in Head and Neck Pathology found that 3.8% of dentinogenic ghost cell tumors harbor duct-like/ cribriform architecture. Herein we discuss this finding regarding the differential diagnosis of this tumor with adenoid ameloblastoma.
Methods:
A critical review of some microscopic findings reported in a recent paper published in the Head and Neck Pathology Journal was done.
Results:
Although there are overlapping microscopic features with dentinogenic ghost cell tumor, adenoid ameloblastoma is distinguished by the combination of duct-like structures and whorls/morules. In our opinion, at least some cases previously diagnosed as dentinogenic ghost cell tumors may now be more accurately classified as adenoid ameloblastoma.
Conclusion:
We conclude that a reassessment of dentinogenic ghost cell tumor cases using the diagnostic criteria proposed by the new WHO classification of Head and Neck Tumors (2022) is warranted.
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