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Published on: December 15, 2011
Pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab-A case report
Mateja Dolenc-Voljč1, Katja Povšič2, Alja Cmok Kučič2
1Department of Dermatovenereology, Faculty of Medicine University of Ljubljana Ljubljana Slovenia.
Abstract:
A patient presented with ulcerations of the buccal mucosae, palate and gingiva. A gingival biopsy confirmed the diagnosis as pemphigus vulgaris. Despite medication with systemic corticosteroids and mycophenolate mofetil, desquamative gingivitis persisted. Adjunct treatment with rituximab was therefore introduced. Regular follow-ups revealed no inflammatory gingival changes even 6 years later.
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