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Updated: Aug 26, 2025

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Preparation of 2,3-Dibromo-1H-indenes and Tetrabromodihydro-s-indacenes as Synthetic Building Blocks
Keisuke Iwata1, Yasunobu Egawa1, Katsunori Yamanishi1
1Department of Chemistry, Faculty of Science, Kanagawa University, Tsuchiya 2946, Hiratsuka 259-1293, Japan.
Abstract:
The acid-induced intramolecular cyclization of 1,1-disubstituted 3-aryl-2,3-dibromoallylalcohols affords 2,3-dibromo-1H-indene derivatives. This method is also applicable to the preparation of tetrabromodihydro-s-indacenes. The thus obtained multi-brominated compounds can serve as versatile synthetic building blocks to obtain a variety of indene and indacene derivatives, as demonstrated by the synthesis of dialkylmethylene-bridged oligo(phenylenevinylene)s, which feature attractive photophysical properties.
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