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Updated: Aug 25, 2025

A Murine Tail Lymphedema Model
Published on: February 10, 2021
Current Concepts in Surgical Management of Lymphedema
Rebecca Knackstedt1, Wei F Chen1
1Department of Plastic Surgery, Center for Lymphedema Research and Reconstruction, Cleveland Clinic, 2049 East 100th Street, A60, Cleveland, OH 44195, USA.
Abstract:
The decision on whom to offer surgical interventions for lymphedema requires collaboration and input from all involved specialists and should address patients' expectations, invasiveness of procedures, and disease severity. There is no consensus on what constitutes success or failure of complex decongestive therapy and when to pursue surgical intervention. Surgery has the potential to fundamentally affect the pathophysiology of the disease state and can be a powerful tool when used correctly. The dogma of which surgery to offer for a given clinical situation has been undergoing revision and is an area of ongoing research.
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