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Chronic Kidney Disease and Post-Percutaneous Coronary Intervention Mortality in Patients With Left Main and

Neil Yager1, Krishnakumar Hongalgi1, Mikhail Torosoff1

  • 1Division of Cardiology and Nephrology, Albany Medical College, Albany, New York.

Texas Heart Institute Journal
|October 20, 2022
PubMed

Insights

Patients with chronic kidney disease (CKD) face higher mortality after nonemergent percutaneous coronary intervention (PCI). Advanced CKD significantly predicts death following PCI for left main coronary artery disease.

Area of Science:

  • Cardiovascular Medicine
  • Nephrology
  • Interventional Cardiology

Background:

  • Chronic kidney disease (CKD) patients are underrepresented in coronary artery disease (CAD) research.
  • Investigating CKD's impact on CAD management outcomes is crucial.

Purpose of the Study:

  • To analyze the effect of CKD on outcomes of elective percutaneous coronary intervention (PCI) for left main or left main-equivalent coronary artery disease.

Main Methods:

  • Analysis of 2,956 elective PCI cases from the New York State Percutaneous Coronary Intervention Registry in 2015.
  • Inclusion criteria: stable left main or equivalent CAD, elective PCI.
  • Exclusion criteria: acute coronary syndromes, shock, prior coronary artery bypass surgery.

Main Results:

  • Stage 4 or 5 CKD was a significant predictor of post-PCI mortality.
  • Congestive heart failure and left main disease also predicted mortality.
  • Outcomes were compared across different degrees of CKD.

Conclusions:

  • Advanced CKD is associated with significantly increased mortality after nonemergent PCI.
  • Findings highlight the heightened risk for CKD patients undergoing PCI for complex CAD.
Abstract

Keywords:
Chronic kidney diseaseleft mainpercutaneous coronary intervention

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