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Updated: Aug 24, 2025

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
Esophageal Cancer Staging
1Department of General Surgery, Hadassah Hebrew University Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Abstract:
Accurate staging is imperative in the management of esophageal cancer Over the years, different treatment modalities have evolved, ranging from endoscopic resection to traditional surgical resection and multimodal approaches, including the addition of chemotherapy, with or without radiation. In this article, we discuss the different stage groups, which guide the clinician in determining staging for esophageal cancer, and subsequent guidance in appropriate treatment modalities for each patient. These groups are based on tumor, node, and metastasis (TNM) staging and have recently been refined into clinical TNM pathologic TNM, and post-neoadjuvant (ypTNM).
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