Related Experiment Video
Updated: Jul 28, 2026
Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens
Published on: December 9, 2022
A Case Report of Pseudomyxoma Peritonei Arising From Primary Mucinous Ovarian Neoplasms
Reuben Joseph1, Ramprasath Sathiamoorthy1, Rajkumar Gnanasekaran1
1Radiology, Chettinad Hospital and Research Institute Chettinad Academy of Research and Education, Chennai, IND.
Abstract:
Pseudomyxoma peritonei (PMP) is a rare manifestation of primary mucinous neoplasms. We report two rare cases of PMP originating from mucinous primary ovarian neoplasms. The case series discusses the cases of female patients aged 86 and 52 years who presented with worsening dyspepsia, abdominal distension, pelvic pain, and altered bowel habits. Both of the patients underwent evaluation comprising cancer antigen-125 (CA-125) levels, ultrasound (US) examination of the abdomen and the pelvis, tumor markers, cytological evaluation, and contrast-enhanced computed tomography (CECT) of the pelvis and abdomen. Patients were diagnosed to have pseudomyxoma peritonei arising from mucinous ovarian tumors. Patients were referred to the surgical department and were successfully managed with repeated removal of mucinous material. The present case report highlights the significant radio-pathologic characteristics of PMP, which originated from mucinous ovarian tumors.
Insights
Pseudomyxoma peritonei (PMP) is a rare condition originating from ovarian tumors. This case series details two patients managed with surgical removal of mucinous material.
Area of Science:
- Oncology
- Gynecologic Oncology
- Pathology
Background:
- Pseudomyxoma peritonei (PMP) is a rare clinical manifestation of primary mucinous neoplasms.
- Primary mucinous ovarian neoplasms are an uncommon origin for PMP.
Observation:
- Two female patients, aged 86 and 52, presented with dyspepsia, abdominal distension, pelvic pain, and altered bowel habits.
- Diagnostic evaluations included cancer antigen-125 (CA-125) levels, ultrasound (US), tumor markers, cytology, and contrast-enhanced computed tomography (CECT).
Findings:
- Both patients were diagnosed with PMP originating from mucinous ovarian tumors.
- Successful management involved repeated surgical debulking of mucinous ascites.
Implications:
- This case report underscores the characteristic radio-pathologic features of PMP arising from ovarian mucinous tumors.
- Highlights the importance of multidisciplinary management for rare gynecologic malignancies.
