[Tick-Borne Encephalitis (TBE) - Clinical and Therapeutical Aspects]

Area of Science:

• Neurology
• Infectious Diseases
• Virology

Context:

• Tick-borne encephalitis (TBE) is an emerging infectious disease affecting the central nervous system.
• The TBE virus is prevalent in expanding regions of Europe and Asia.
• TBE presents a significant public health challenge due to its potential for severe neurological complications.

Purpose:

• To review the clinical and therapeutic aspects of Tick-Borne Encephalitis (TBE).
• To highlight diagnostic criteria and patient outcomes.
• To emphasize the importance of preventive measures.

Summary:

• TBE is an acute inflammatory disease of the CNS caused by the TBE virus, with symptomatic infections occurring in only 2-30% of cases.
• Clinical manifestations range from meningitis to meningoencephalomyelitis, with prognosis varying based on the affected CNS area.
• Diagnosis relies on detecting TBEV-specific antibodies and inflammatory CSF syndrome. Recovery rates are high for meningitis but lower for encephalitis and myelitis.

Impact:

• TBE vaccination is the primary preventive strategy for individuals aged 6 and above in endemic areas.
• Understanding TBE's clinical spectrum and outcomes is vital for patient management.
• The study underscores the need for continued vigilance and preventive measures against TBE virus transmission.