QUANTITATIVE CHARACTERISTICS OF GUT MICROBIOTA IN PATIENTS WITH ARTERIAL HYPERTENSION

The aim of the work is to study the quantitative characteristics of gut microbiota (GM) in patients with arterial hypertension AH - residents of Ukraine in comparison with practically healthy individuals. 36 patients with AH stage II, 2-3 degrees against the background of normal body weight were examined. The control group consisted of 20 apparently healthy individuals. The examination included standard clinical, laboratory and instrumental methods. For determination of the quantitative composition of GM were used the method of polymerase chain reaction with hybridization-fluorescence detection of results in real time and the test system "COLONOFLOR-16 (biocenosis)" ("ALFALAB"). Statistical analysis of the results was carried out by standard methods using Microsoft Excel 17.0. The significant changes in GM quantitative characteristics were found in patients with AH (resident of Ukraine) in comparison with healthy individuals: a significant decrease in the number of Lactobacillus spp., Bifidobacterium spp. and Faecalibacterium prausnitzii. The deficiency of Lactobacillus spp., Bifidobacterium spp. and Faecalibacterium prausnitzii in patients with AH - residents of Ukraine may indicate the important role of GM disorders in the pathogenesis of hypertension.