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Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate
Published on: April 24, 2018
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Pyridine-4-carboxamidoxime N-oxide
Clifford W Padgett1, Kirkland Sheriff1, Will E Lynch1
1Georgia Southern University, 11935 Abercorn St., Department of Chemistry and Biochemistry, Savannah GA 31419, USA.
Iucrdata
|November 7, 2022
Summary
We report the first crystal structure of pyridine-4-carboxamidoxime N-oxide, a compound synthesized during metal-organic framework research. This molecule forms layered structures through specific hydrogen bonding interactions.
Area of Science:
- Materials Science
- Crystallography
- Organic Chemistry
Background:
- Metal-organic frameworks (MOFs) are synthesized using organic N-oxides.
- Pyridine-4-carboxamidoxime N-oxide is a novel compound within this research area.
Purpose of the Study:
- To determine the crystal structure of pyridine-4-carboxamidoxime N-oxide.
- To analyze the intermolecular interactions and crystal packing.
Main Methods:
- Single-crystal X-ray diffraction was employed to elucidate the crystal structure.
- Analysis of hydrogen bonding and molecular geometry was performed.
Main Results:
- The first crystal structure of pyridine-4-carboxamidoxime N-oxide (C6H7N3O2) is reported.
- The hydroxy-carbamimidoyl group is nearly coplanar with the pyridine ring.
- The compound forms hydrogen-bonding layers stabilized by O-H⋯O and N-H⋯O interactions, creating R34(24) ring motifs.
- No π-π interactions were observed in the crystal structure.
Conclusions:
- The crystal structure reveals specific hydrogen bonding patterns essential for layer formation.
- This study provides fundamental structural insights into pyridine-4-carboxamidoxime N-oxide relevant to MOF synthesis.
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