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Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
Published on: November 24, 2014
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A different technique for sutureless coronary bypass grafting.
Tamás Ruttkay1, László Bárány1, András Grimm1,2
1Laboratory for Applied and Clinical Anatomy, Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest, Hungary.
Interventional Medicine & Applied Science
|November 7, 2022
Summary
A novel stent-based technique for coronary artery anastomosis offers a fast and reliable method for distal coronary artery bypass surgery. This ex-vivo study demonstrates its feasibility, paving the way for endoscopic applications.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Medical Devices
Background:
- Manual suturing in coronary artery bypass grafting (CABG) is time-consuming and technically demanding.
- Existing automated coronary anastomotic devices have not achieved widespread clinical adoption.
- There is a need for simpler, faster, and more reliable methods for distal coronary anastomosis.
Purpose of the Study:
- To develop and evaluate an easy, fast, and reliable endoluminal vessel-to-vessel stent bridge distal anastomotic technique.
- To assess the feasibility of using a stent fixation method for coronary anastomosis.
- To provide a potential alternative to manual suturing in coronary surgery.
Main Methods:
- The study utilized ten coronary arteries from eight fresh human hearts for ex-vivo analysis.
- Anastomosis was achieved by implanting a graft vessel into the coronary artery lumen using stent fixation.
- Technique evaluation included intraluminal endoscopy, functional streaming tests, and vessel coloring for durability and conductibility assessment.
Main Results:
- The developed anastomotic technique yielded excellent results in all tested cases.
- No instances of obstruction, dissection, or dislocation of the vessels were observed.
- The ex-vivo assessment confirmed the patency and integrity of the anastomoses.
Conclusions:
- The described stent-based technique is feasible for ex-vivo endoscopic distal coronary artery anastomosis.
- This method presents a potentially easy, fast, and reliable approach for coronary surgery.
- Further development of adapted stents and in-vivo testing are crucial for future clinical application.

