Cardiovascular Pharmacology.

Jessica M Mason1, Michael E O'Brien2, Jennifer L Koehl3

  • 1Department of Pharmacy, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.

Summary

This review covers essential pharmacologic therapies for cardiovascular emergencies like acute coronary syndromes, heart failure, and arrhythmias. It offers practical guidance for Emergency Department clinicians managing these critical conditions.

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Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

Cardiovascular Drugs: Classification based on Therapeutic Indications

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Pathophysiology of Cardiac Performance01:29

Pathophysiology of Cardiac Performance

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Cardiomyopathy V: Interprofessional Care

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Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

Cardiopulmonary Resuscitation IV: Pharmacological Management

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Heart Failure Drugs: β-Blockers01:22

Heart Failure Drugs: β-Blockers

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Antianginal Drugs: Nitrates and β-Blockers01:16

Antianginal Drugs: Nitrates and β-Blockers

In cardiovascular health, antianginal drugs combat angina pectoris — a condition marked by chest pain owing to diminished blood flow to the heart.
Organic nitrates,  such as nitroglycerin, play a pivotal role. Once metabolized, they liberate nitric oxide, a molecular marvel. Nitric oxide triggers guanylyl cyclase and augments cGMP production. This biochemical cascade orchestrates the relaxation of vascular smooth muscles, ushering in vasodilation and enhancing coronary blood flow....
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