Related Experiment Video
Updated: Aug 20, 2025
12:00
Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
Published on: April 8, 2009
10.4K
Clinical Manifestations of Monkeypox
Haneen Abaza1,2, Kuchalambal Agadi2,3, Ayush Anand2,4
1King Hussein Cancer Center, Amman, Jordan.
Advances in Experimental Medicine and Biology
|November 17, 2022
Summary
Monkeypox, a global health concern caused by the monkeypox virus, presents with a characteristic rash and potential systemic symptoms. Diagnosis relies on real-time polymerase chain reaction, with management focusing on monitoring and supportive care.
Area of Science:
- Virology
- Public Health
- Dermatology
Background:
- Monkeypox virus (MPXV) poses a significant global health challenge.
- Transmission occurs via respiratory secretions, direct contact with lesions, or contaminated objects.
- The virus disproportionately affects homosexual men, with many cases being asymptomatic.
Purpose of the Study:
- To provide a comprehensive overview of monkeypox.
- To detail diagnostic approaches and clinical manifestations.
- To outline current management strategies for monkeypox.
Main Methods:
- Literature review of monkeypox epidemiology, transmission, and clinical presentation.
- Discussion of diagnostic methods, including real-time polymerase chain reaction (PCR).
- Analysis of treatment and management strategies for monkeypox complications.
Main Results:
- Monkeypox presents with a prodromal phase followed by a distinctive exanthematous rash evolving over three weeks.
- Associated symptoms include lymphadenopathy, respiratory issues, neurological involvement (encephalitis), and ocular complications.
- Real-time PCR is the gold standard for diagnosis; clinical history is crucial in its absence.
Conclusions:
- Effective management of monkeypox involves vigilant monitoring, antiviral therapy, and addressing complications.
- Early recognition and diagnosis are critical for controlling the spread of monkeypox.
- Continued research is needed to fully understand and combat monkeypox outbreaks.
Related Concept Videos
01:25Endocarditis II: Clinical Features of Infective Endocarditis
21
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
21
01:31Pulmonary Tuberculosis III
412
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
412
01:26Stages of Infection
58.3K
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
58.3K
01:30Skin Cancer
4.4K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.4K
01:26Pulmonary Tuberculosis IV
186
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
186
01:30Coronary Artery Disease III: Clinical Manifestations
25
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
25