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Anticoagulation and Antiplatelet Agents in Peripheral Arterial Interventions

Jordan Taylor1, Henry R Stiepel1, Nicole Keefe1

  • 1Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

Seminars in Interventional Radiology
|November 21, 2022
PubMed

Insights

Effective peripheral artery disease revascularization requires careful management of clotting. Post-procedure care involves selecting appropriate anticoagulant and antiplatelet agents based on patient factors to improve cardiovascular outcomes.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Pharmacology

Background:

  • Peripheral artery disease (PAD) revascularization necessitates precise control of the clotting cascade.
  • Post-procedural management is critical for optimizing patient outcomes and preventing complications.

Purpose of the Study:

  • To guide interventionalists in selecting appropriate pharmacotherapy for post-revascularization management.
  • To review anticoagulant and antiplatelet agents for patients with peripheral artery disease.

Main Methods:

  • Review of current literature on anticoagulant and antiplatelet therapies.
  • Discussion of patient-specific factors influencing medication choice, including cardiovascular risk, contraindications, and psychosocial elements.

Main Results:

  • Effective revascularization depends on periprocedural pharmacological regulation.
  • Individualized treatment plans considering patient factors are essential for post-revascularization care.
  • Familiarity with available medication classes is crucial for improving cardiovascular outcomes.

Conclusions:

  • Optimal post-revascularization management requires a tailored approach to pharmacotherapy.
  • Anticoagulant and antiplatelet agents play a vital role in improving outcomes for PAD patients.
  • Interventionalists must be knowledgeable about medication options to enhance patient cardiovascular health.

Keywords:
anticoagulantantiplateletdual-antiplatelet therapyinterventional radiologyperipheral artery disease

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