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Updated: Aug 20, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Preoperative Systemic Therapy for Breast Cancer
Abhigna Kodali1, Vijayakrishna K Gadi2
1Division of Hematology and Oncology, Maimonides Cancer Center, 6300 Eight Avenue, Brooklyn, NY 11220, USA.
Abstract:
The indications for preoperative/neoadjuvant systemic therapy in breast cancer have changed over the past few years. In this article, the authors review the current data for use of neoadjuvant therapy in inoperable and operable settings. The evolution of various neoadjuvant regimens used in triple-negative breast cancer, human epidermal growth factor receptor 2 (HER2) overexpressing/gene-amplified (HER2+) tumors, and hormone receptor positive breast cancer is discussed as well as the role of neoadjuvant chemotherapy in tailoring adjuvant treatment.
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