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Updated: Aug 20, 2025

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Advances in Endocrine Surgery.

Michael S Lui1, Aditya S Shirali1, Bernice L Huang1

  • 1Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

Surgical Oncology Clinics of North America
|November 21, 2022
PubMed
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Endocrine surgery is evolving, favoring less invasive options like thyroid lobectomy for low-risk papillary thyroid cancer and minimally invasive parathyroidectomy. New therapies are also improving parathyroid cancer and adrenal tumor management.

Area of Science:

  • Endocrine Surgery
  • Surgical Oncology
  • Oncology

Background:

  • The management of endocrine diseases has seen significant advancements.
  • Traditional approaches are being refined with new techniques and therapies.
  • Patient selection and risk stratification are crucial in endocrine surgery.

Purpose of the Study:

  • To summarize recent key advancements in endocrine surgery.
  • To highlight shifts towards less invasive procedures.
  • To outline improvements in managing thyroid cancer, parathyroid conditions, and adrenal tumors.

Main Methods:

  • Review of recent literature and clinical practice changes in endocrine surgery.
  • Analysis of trends in thyroidectomy, parathyroidectomy, and adrenal surgery.
Keywords:
Adrenocortical carcinomaCushing’s syndromeHyperparathyroidismLymph node dissectionPapillary thyroid cancerParathyroid carcinomaPheochromocytomaThyroid lobectomy

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  • Incorporation of data on novel therapeutic strategies for endocrine malignancies.

    • Main Results:

    • Thyroid lobectomy is increasingly adopted for low-risk papillary thyroid cancer, moving away from universal total thyroidectomy.
    • Minimally invasive parathyroidectomy, with or without intraoperative monitoring, is standard for well-localized primary hyperparathyroidism.
    • Parathyroid cancer management is enhanced by immune checkpoint blockade and targeted therapies.
    • Minimally invasive techniques are now applied to benign adrenal tumors and selected secondary adrenal malignancies.

    Conclusions:

    • Endocrine surgery is embracing minimally invasive approaches and personalized medicine.
    • These advancements offer improved outcomes and tailored treatments for endocrine conditions.
    • The field continues to evolve, prioritizing less invasive and more effective interventions.