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Squamous Cell Carcinoma: An Update in Staging, Management, and Postoperative Surveillance Strategies
Anthony K Guzman1, Chrysalyne D Schmults1, Emily S Ruiz1
1Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Dermatologic Clinics
|November 21, 2022
Summary
Cutaneous squamous cell carcinoma (cSCC) is increasing. This review updates the diagnosis and management of high-risk cSCC, focusing on staging, imaging, and adjuvant therapy for better patient outcomes.
Area of Science:
- Dermatology and Oncology
- Public Health
Background:
- Rising incidence of cutaneous squamous cell carcinoma (cSCC) constitutes a significant public health concern.
- While surgical excision cures most cSCC, high-risk cases necessitate advanced management strategies.
Purpose of the Study:
- To provide an evidence-based update on the current diagnosis and management of cSCC.
- To discuss key research areas including prognostic staging, radiologic imaging, and adjuvant therapy for high-risk cSCC.
Main Methods:
- Review of current literature and evidence-based guidelines.
- Analysis of prognostic factors and staging systems for cSCC.
- Evaluation of the role of imaging and adjuvant therapies in cSCC management.
Main Results:
- Accurate staging is crucial for high-risk cSCC.
- Multimodal therapy, including imaging and adjuvant treatments, is essential for managing complex cases.
- Ongoing research focuses on refining prognostic models and therapeutic approaches.
Conclusions:
- A coordinated strategy involving accurate staging, multimodal therapy, and surveillance is vital for high-risk cSCC.
- Further research is needed to optimize prognostic staging and the use of radiologic imaging and adjuvant therapy.
