Jove
Visualize
Contact Us

Related Concept Videos

Transdermal Drug Delivery Systems01:18

Transdermal Drug Delivery Systems

Transdermal drug delivery systems (TDDS) enable the controlled release of drugs across the skin into systemic circulation. They are particularly advantageous for drugs with short half-lives or narrow therapeutic indices, as they maintain consistent plasma concentrations and reduce the risk of subtherapeutic or toxic levels.TDDS are categorized into monolithic, reservoir, and mixed systems. Monolithic systems embed the drug in a polymer matrix, where diffusion governs release. Reservoir systems...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tuning the Mechanical Properties of Crosslinked Copolymers via Sequence and Solvent-Selective Swelling for Vat Photopolymerization.

Angewandte Chemie (International ed. in English)·2026
Same author

High-Resolution 3D Bioprinted Hydrogel Scaffolds Enable Sustained Intraperitoneal Cell Delivery.

Molecules (Basel, Switzerland)·2026
Same author

Preformulated, Shelf-Stable, Dendritic Cell-Targeting Nanogel mRNA Vaccine Delivery Platform.

Bioconjugate chemistry·2026
Same author

A 3D-Printed Scaffolded Hydrogel Microneedle Array Biosensor for Real-Time, Continuous Monitoring.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Continuous monitoring of blood-interstitial fluid intercompartmental molecular kinetics in freely moving animals.

Science advances·2026
Same author

Engineered 3D-Lattice Microneedle Array Patches for Enhanced Nanovaccine Delivery to Dendritic Cells in Cancer Immunotherapy.

ACS nano·2026
Same journal

DeepDOX1: A Dual-Drive Framework Integrating Deep Learning and First-Principles Quantum Chemistry for Drug-Protein Affinity Prediction.

JACS Au·2026
Same journal

Catalyst-Controlled Regiodivergent C-H Olefination of Furanyl Carbamates through a Rational Approach.

JACS Au·2026
Same journal

Charting the Biosynthetic Landscape of Hybrid Polyketide-Nonribosomal Peptide-Specialized Lipids.

JACS Au·2026
Same journal

Valence-State-Dependent Surface Lattice Oxygen in CeO<sub>2</sub>‑Modified VPO Catalysts: Elucidating the Mechanism of <i>n</i>‑Butane Selective Oxidation to Maleic Anhydride.

JACS Au·2026
Same journal

Quantitative Insights into Pressure-Dependent Mass Transport and Reaction Kinetics in Electrochemical CO<sub>2</sub> Reduction.

JACS Au·2026
Same journal

3‑Methylthiopropionic Acid Kills Carbapenem-Resistant <i>Klebsiella pneumoniae</i> by Disrupting Membrane Integrity and Bioenergetics.

JACS Au·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 25, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.5K

3D-Printed Microarray Patches for Transdermal Applications.

Netra U Rajesh1, Ian Coates2, Madison M Driskill2

  • 1Department of Bioengineering, Stanford University, Stanford, California94305, United States.

JACS Au
|December 5, 2022
PubMed
Summary
This summary is machine-generated.

3D printing enables advanced microneedle array patches (MAPs) for minimally invasive drug delivery and diagnostics. This technology allows for precise, scalable manufacturing of novel MAP designs for enhanced therapeutic and diagnostic applications.

More Related Videos

Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.2K
3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening
11:28

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening

Published on: October 4, 2017

10.4K

Related Experiment Videos

Last Updated: Jun 25, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.5K
Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.2K
3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening
11:28

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening

Published on: October 4, 2017

10.4K

Area of Science:

  • Biomaterials Science
  • Drug Delivery Systems
  • 3D Printing Technology

Background:

  • The intradermal (ID) space is a promising site for minimally invasive drug delivery and diagnostics.
  • Current microneedle array patches (MAPs) face manufacturing limitations hindering innovation and scalability.
  • Existing fabrication methods restrict the design complexity and geometric tunability of MAPs.

Purpose of the Study:

  • To introduce a novel 3D printing approach for advanced MAP fabrication.
  • To explore the potential of continuous liquid interface production (CLIP) for MAP development.
  • To demonstrate the creation of new MAP designs for versatile cargo delivery and fluid sampling.

Main Methods:

  • Utilized high-resolution continuous liquid interface production (CLIP) 3D printing.
  • Employed light and oxygen to facilitate rapid, noncontact polymerization for MAP manufacturing.
  • Engineered novel lattice MAPs (L-MAPs) and dynamic MAPs (D-MAPs) with precise geometries.

Main Results:

  • CLIP 3D printing enables rapid and scalable production of MAPs.
  • Achieved precise and tunable geometries for innovative MAP designs.
  • Successfully produced L-MAPs and D-MAPs capable of delivering solid/liquid cargos and sampling interstitial fluid.

Conclusions:

  • Additive manufacturing, specifically CLIP 3D printing, revolutionizes MAP development.
  • This technology opens new avenues for advanced minimally invasive drug delivery and diagnostic platforms.
  • The developed MAPs offer enhanced capabilities for therapeutic and diagnostic applications.