Nomogram to Predict Radiation Enteritis in Cervical Squamous Cell Carcinoma.

Area of Science:

• Oncology
• Radiation Oncology
• Gastroenterology

Background:

• Radiotherapy is a primary treatment for cervical cancer.
• Radiation enteritis is a common and debilitating side effect of pelvic radiotherapy.
• Identifying risk factors is crucial for prevention and management.

Purpose of the Study:

• To investigate the risk factors associated with radiation enteritis in cervical cancer patients receiving radiotherapy.
• To develop a predictive model for radiation enteritis.

Main Methods:

• Retrospective analysis of 90 cervical cancer patients.
• Comparison between patients with and without radiation enteritis.
• Univariate and multivariate logistic regression to identify independent risk factors.
• Construction and evaluation of a nomogram prediction model.

Main Results:

• The incidence rate of radiation enteritis was 35.56%.
• Independent risk factors identified include low hemoglobin, low albumin, and low total T lymphocyte count.
• The developed nomogram model showed good predictive efficiency and differentiation.

Conclusions:

• Hemoglobin, albumin, and total T lymphocyte count are significant risk factors for radiation enteritis in cervical cancer patients.
• The nomogram model provides a valuable tool for predicting radiation enteritis risk, aiding clinical decision-making.