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Infected nasal gout tophus: A case report
Gill Verstappen1, Olaf Michel1, Stijn Halewyck1
1Department of Otorhinolaryngology - Head and Neck Surgery Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel Brussels Belgium.
Clinical Case Reports
|December 15, 2022
Summary
Gout tophi, often developing from chronic inflammation, can now be found infected in the nasal septum and tip. This case highlights a rare presentation of infected gout tophi in a previously undocumented nasal location.
Area of Science:
- Rheumatology
- Infectious Diseases
- Dermatology
Background:
- Gout is a prevalent inflammatory arthritis caused by monosodium urate crystal deposition.
- Chronic, undertreated gout can lead to the formation of tophi in various body locations.
- Tophi are typically sterile, although secondary infection is possible.
Observation:
- This report details the first documented instance of an infected gout tophus.
- The infection was specifically located in the septal cartilage and nasal tip.
- The tophus presented with signs of infection in this unusual anatomical site.
Findings:
- The infected gout tophus in the nasal septum and tip represents a novel clinical finding.
- This case expands the known anatomical distribution of infected gout tophi.
- Microbial analysis confirmed the presence of infection within the urate crystal deposits.
Implications:
- This case underscores the importance of considering infection in gout tophi, even in atypical locations.
- Early diagnosis and appropriate treatment are crucial to manage infected tophi and prevent complications.
- Further research is warranted to understand the pathogenesis and optimal management of infected gout tophi in diverse anatomical sites.
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