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[Gastrointestinal microecology in internal medicine]
1Klinik und Poliklinik für Innere Medizin des Bereichs Medizin, Ernst-Moritz-Arndt-Universität Greifswald, DDR.
Abstract:
Gastrointestinal microecology is a field with highest integrative pretension. Its clinical actuality is reflected in numerous diseases. Colonization anomalies may become relevant particularly in the case of microbial overgrowth-syndrome. Due to recent experimental results, intestinal microbes are gaining a certain importance with respect of the utilization of hard- or non-absorbable carbohydrates. With regard to a further thinking over the conception of selective decontamination gastrointestinal microecology is challenged, too. Hitherto, the various microbial alterations of drugs and contaminants got little consideration. A microbial participation in the genesis of chronic inflammatory intestinal diseases as well as of carcinoma of the colon becomes subject of discussion, increasingly.
Insights
Gastrointestinal microecology impacts numerous diseases, especially microbial overgrowth syndrome. Intestinal microbes are increasingly recognized for their role in utilizing complex carbohydrates and potentially contributing to inflammatory bowel diseases and colon cancer.
Area of Science:
- Gastrointestinal microecology and its clinical relevance.
Context:
- Colonization anomalies are significant in microbial overgrowth syndrome.
- Intestinal microbes play a role in the utilization of hard-to-digest carbohydrates.
Purpose:
- To highlight the growing importance of gastrointestinal microecology.
- To address the consideration of microbial alterations from drugs and contaminants.
- To discuss the potential microbial involvement in chronic inflammatory intestinal diseases and colon cancer.
Summary:
- Gastrointestinal microecology is a highly integrative field with significant clinical implications.
- Anomalies in gut microbial colonization are particularly relevant in microbial overgrowth syndrome.
- Recent research emphasizes the role of intestinal microbes in carbohydrate metabolism and potential links to gastrointestinal diseases.
Impact:
- The study challenges current concepts in selective decontamination of the gastrointestinal tract.
- It underscores the need to consider microbial alterations induced by drugs and contaminants.
- It highlights the increasing discussion around microbial participation in the development of chronic inflammatory intestinal diseases and colon cancer.