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The Pakistan Brain Tumour Epidemiology Study
Syed Ather Enam1, Mashal Murad Shah1, Mohammad Hamza Bajwa1
1The Aga Khan University Hospital, Karachi,Pakistan.
JPMA. the Journal of the Pakistan Medical Association
|January 2, 2023
Summary
This study analyzed 2750 brain tumour cases in Pakistan, finding gliomas most common. Hypertension and smoking were frequent risk factors, with low metastasis rates observed.
Area of Science:
- Neuro-oncology
- Epidemiology
- Public Health
Background:
- Brain tumours represent a significant health concern globally.
- Understanding the epidemiology of brain tumours in specific regions like Pakistan is crucial for targeted interventions.
- Limited data exists on the prevalence and risk factors of brain tumours within Pakistan.
Purpose of the Study:
- To determine the epidemiology of brain tumours in Pakistan.
- To identify potential associated risk factors, including family, medical, and social characteristics.
- To establish national prevalence and incidence rates for brain tumours.
Main Methods:
- A retrospective, cross-sectional, nationwide study was conducted.
- Data was collected for brain tumour cases diagnosed between January 1, 2019, and December 31, 2019.
- All age groups and histopathology types were included to capture comprehensive data.
Main Results:
- A total of 2750 brain tumour cases were recorded, with 69% diagnosed in the public sector.
- Gliomas were the most common type (28.29%), while pineal tumours were least common (0.69%).
- Hypertension (51.89%) and smoking (62.02%) were the most frequent co-morbidity and social behavior, respectively. Median age at diagnosis was 36 for males and 37 for females.
Conclusions:
- The Pakistan Brain Tumour Epidemiology Study (PBTES) and Pakistan Brain Tumour Classification (PBTC) provide a platform for improved cancer care.
- Strengthening cancer care health systems, implementing treatment guidelines, and regular cancer registration are recommended.
- The study highlights the need for continued research and collaborative efforts in neuro-oncology within Pakistan.

