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Updated: Aug 15, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Current topic of vascular function in hypertension
Tatsuya Maruhashi1, Yukihito Higashi2,3
1Department of Regenerative Medicine, Division of Radiation Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan. maru0512@hiroshima-u.ac.jp.
Insights
Vascular function tests help evaluate atherosclerosis and cardiovascular risk. This review covers new findings on vascular function, its link to COVID-19, and lifestyle impacts.
Area of Science:
- Cardiovascular Medicine
- Vascular Biology
- Hypertension Research
Background:
- Vascular function assessment aids in evaluating atherosclerosis severity and cardiovascular risk stratification.
- Understanding vascular dysfunction is key to understanding cardiometabolic disorders.
- Despite COVID-19 challenges, significant research on vascular function was published in 2020-2021.
Purpose of the Study:
- To review recent findings on vascular function.
- To discuss the relationship between vascular function and COVID-19.
- To highlight the role of lifestyle modifications and vascular function tests in managing cardiovascular risk.
Main Methods:
- Literature review of recent publications in hypertension and cardiovascular journals.
- Synthesis of new findings on vascular function assessment.
- Discussion of clinical implications for cardiovascular risk management.
Main Results:
- Vascular function tests provide valuable information for atherosclerosis evaluation and risk stratification.
- Associations between vascular dysfunction and cardiometabolic disorders are increasingly understood.
- New insights link vascular function to COVID-19 and emphasize lifestyle interventions.
Conclusions:
- Vascular function assessment is crucial for managing cardiovascular risk factors like hypertension.
- Lifestyle modifications are vital for maintaining vascular health.
- This review offers practical insights for clinical practice regarding vascular function and cardiovascular disease management.
Abstract:
Vascular function assessment is useful for the evaluation of atherosclerosis severity, which may provide additional information for cardiovascular risk stratification. In addition, vascular function assessment is helpful for a better understanding of pathophysiological associations between vascular dysfunction and cardiometabolic disorders. In 2020 and 2021, although coronavirus disease 2019 (COVID-19) was still a worldwide challenge for health care systems, many excellent articles regarding vascular function were published in Hypertension Research and other major cardiovascular and hypertension journals. In this review, we summarize new findings on vascular function and discuss the association between vascular function and COVID-19, the importance of lifestyle modifications for the maintenance of vascular function, and the usefulness of vascular function tests for cardiovascular risk assessment. We hope this review will be helpful for the management of cardiovascular risk factors, including hypertension and cardiovascular diseases, in clinical practice.
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