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Updated: Aug 15, 2025

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
Development of a three-dimensional dose evaluation method for computed tomography.
Toshizo Katsuda1, Rumi Gotanda2, Tatsuhiro Gotanda2
1Medical radiation technology, Shizuoka College of Medicalcare Science, Hamamatsu-city, Shizuoka, Japan.
This study developed a method to create 3D dose maps using computed tomography (CT) phantoms and radiochromic film. The technique enables detailed 3D radiation dose distribution analysis for improved medical imaging accuracy.
Area of Science:
- Medical Physics
- Radiological Imaging
- Radiation Dosimetry
Background:
- Computed tomography (CT) scans involve an X-ray tube orbiting a patient.
- Two-dimensional (2D) dose distributions can be visualized using radiochromic film in phantoms.
- Three-dimensional (3D) dose mapping is crucial for accurate radiation therapy planning and quality assurance.
Purpose of the Study:
- To evaluate the concept and methodology for creating a 3D dose map.
- To develop a phantom system using radiochromic film for 3D dose distribution acquisition.
- To assess coronal and axial plane dose distributions within CT phantoms.
Main Methods:
- Utilized half-cylindrical acrylic phantoms (10 and 16 cm diameter, 30 cm length) with sandwiched radiochromic film.
- Acquired 2D dose distribution images using an XR-QA2 film, image scanner, and processing software.
- Reconstructed 3D dose distribution by rotating 2D data and applying image processing techniques to the red channel of the film image.
Main Results:
- Successfully generated a 3D pixel value map representing dose distribution.
- Demonstrated the feasibility of creating cross-sectional color images from processed 2D data.
- Developed a reproducible dose measurement procedure for 3D dose distribution using the phantom system.
Conclusions:
- The developed methodology provides a viable approach for constructing 3D dose maps from CT scans.
- This technique enhances the ability to analyze complex radiation dose distributions in medical imaging.
- The study establishes a foundation for advanced phantom-based dosimetry in CT applications.
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