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Diagnostic assessment of diabetic microangiopathy by tcPO2 stimulation tests
N Weindorf1, U Schultz-Ehrenburg, P Altmeyer
1Department of Dermatology, St. Josef-Hospital, Ruhr-University Bochum.
Abstract:
Transcutaneous PO2 measurements at 37 degrees C can recognize and quantify diabetic microangiopathy if suitable stimulation tests are used. The following parameters are of practical importance: resting PO2, postocclusive PO2, rubefacient-induced PO2 and 45 degrees C heating PO2. Patients with diabetic microangiopathy show diminished PO2 values in rubefacient-induced PO2 and 45 degrees C heating PO2. The former ist probably related to endothelial-cell function disturbances and the letter to organic vessel wall changes. Thus, a quantitative and differentiated picture of microangiopathy can be obtained in each individual patient.