Therapy for Stage IV Non-Small-Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline, Version 2022.3

Area of Science:

• Oncology
• Clinical Practice Guidelines

Background:

• Clinical practice guidelines require frequent updates due to rapidly evolving evidence.
• The American Society of Clinical Oncology (ASCO) addresses this need with living guidelines.

Purpose of the Study:

• To describe the methodology and framework for ASCO Living Guidelines.
• To outline the process for continuous systematic literature review and guideline updates.

Main Methods:

• Development of living guidelines for rapidly evolving topic areas.
• Regular updates by a standing expert panel.
• Continuous systematic review of health literature.

Main Results:

• ASCO Living Guidelines are updated on a regular schedule.
• The process adheres to the ASCO Guidelines Methodology Manual and Conflict of Interest Policy.
• Updates are published regularly and accessible online.

Conclusions:

• Living guidelines provide a dynamic approach to clinical recommendations.
• These guidelines support evidence-based practice in rapidly changing fields.
• ASCO Living Guidelines are a resource for clinicians and patients, complementing professional judgment.