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Related Concept Videos

Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

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Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
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Organometallic compounds are compounds that contain a carbon–metal bond. Carbon belongs to an organyl group like alkyl, aryl, allyl, or benzyl groups. The metal can be from Group I or Group II of the periodic table, a transition metal, or a semimetal.
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Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
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Related Experiment Video

Updated: Aug 7, 2025

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
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Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks

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Virus Management Using Metal-Organic Framework-Based Technologies.

Léo Boivin1, Pierre D Harvey1

  • 1Département de Chimie, Université de Sherbrooke, Québec J1K 2R1, Canada.

ACS Applied Materials & Interfaces
|March 9, 2023
PubMed
Summary
This summary is machine-generated.

Metal-organic frameworks (MOFs) are versatile nanomaterials used to combat viruses like SARS-CoV-2 and HIV-1. Various MOF strategies, including sequestration and drug delivery, offer promising solutions for viral management and protection.

Keywords:
Metal−organic frameworkantiviraldrug deliveryphotocatalysisvirusvirus mineralization

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Area of Science:

  • Nanotechnology
  • Materials Science
  • Virology

Background:

  • Viral infections pose significant global health threats.
  • Developing effective antiviral strategies is crucial for public health.
  • Metal-organic frameworks (MOFs) show potential as antiviral agents.

Purpose of the Study:

  • To review strategies utilizing nanoscale MOFs for viral management.
  • To highlight MOF applications against various viruses, including SARS-CoV-2, HIV-1, and tobacco mosaic virus.
  • To discuss diverse MOF-based antiviral mechanisms.

Main Methods:

  • Sequestration of viruses via host-guest encapsulation within MOF pores.
  • Mineralization of viruses using MOF materials.
  • Creation of physical barriers with MOFs to impede viral spread.
  • Controlled delivery of antiviral drugs and bioinhibitors using MOFs.
  • Photosensitization of singlet oxygen by MOFs for viral inactivation.
  • Direct viral inactivation through contact with cytotoxic MOFs.

Main Results:

  • Nanoscale MOFs demonstrate efficacy in managing and neutralizing various viruses.
  • Multiple MOF-based strategies offer versatile approaches to antiviral therapy.
  • MOFs can be engineered for targeted viral sequestration, drug delivery, and direct inactivation.

Conclusions:

  • Nanoscale MOFs represent a promising platform for developing novel antiviral interventions.
  • The diverse mechanisms of MOF-based antiviral strategies warrant further investigation.
  • MOFs offer a versatile toolkit for combating viral infections and diseases.