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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
Electrochemical Dearomative Spirocyclization
Nan Li1, Zhaojiang Shi1, Wei-Zhen Wang1
1Key Laboratory of Molecule Synthesis and, Function Discovery (Fujian Province University), College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Abstract:
Electrochemical dearomative spirocyclization serves as a green and sustainable approach to convert the flat, two-dimension aromatic feedstock into the value-added three-dimension spirocyclic architectures. This review highlights the recent advances, emphasizes mechanistic discussions, and showcases synthetic applications of this emerging versatile and powerful transformation.
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