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Related Experiment Video

Updated: Aug 6, 2025

Preparation of Pseudo-Typed H5 Avian Influenza Viruses with Calcium Phosphate Transfection Method and Measurement of Antibody Neutralizing Activity

Preparation of Pseudo-Typed H5 Avian Influenza Viruses with Calcium Phosphate Transfection Method and Measurement of Antibody Neutralizing Activity

Published on: November 22, 2021

Pseudotyped Virus for Henipavirus.

Tao Li¹, Ziteng Liang¹, Weijin Huang¹

¹Division of HIV/AIDS and Sex-transmitted Virus Vaccines, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.

Advances in Experimental Medicine and Biology

|March 15, 2023

Summary

This summary is machine-generated.

Pseudotyped viruses mimic Nipah virus (NiV) and Hendra virus (HeV) for safer research. These tools advance studies on viral entry and drug development, enabling work outside high-containment labs.

Keywords:

Henipavirus Membrane fusion Packaging system Pseudotyped virus Receptor

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Published on: March 1, 2019

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Last Updated: Aug 6, 2025

Preparation of Pseudo-Typed H5 Avian Influenza Viruses with Calcium Phosphate Transfection Method and Measurement of Antibody Neutralizing Activity

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Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses

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Published on: January 15, 2020

Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting

Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting

Published on: March 1, 2019

Area of Science:

Virology
Infectious Diseases
Biotechnology

Background:

Henipavirus (HNV) genus includes highly virulent Nipah virus (NiV) and Hendra virus (HeV).
These viruses are WHO-priority pathogens requiring Biosafety Level 4 containment.
Research on HNV mechanisms and countermeasures is crucial for public health.

Conclusions:

Pseudotyped virus systems offer a safer and more accessible platform for HNV research.
They are invaluable tools for understanding viral pathogenesis and developing therapeutics.
Continued development of these systems will accelerate HNV countermeasure discovery.