Related Experiment Video
Updated: Aug 6, 2025

12:48
The Multifaceted Benefits of Protein Co-expression in Escherichia coli
Published on: February 5, 2015
12.1K
Approximation of circle number π by spread-plating Escherichia coli
Florian Schiffel1, Stephan Noll1
1Biotechnology Department, Faculty of Life Sciences, Hamburg University of Applied Sciences (HAW Hamburg), Hamburg, Germany.
Abstract:
Ideally, microbial spread plating results in randomly distributed colonies on the agar surface. This can be seen as a Monte Carlo simulation and enables probabilistic approximation of circle number π. We perform π approximation in a microbiology undergraduate course to awaken the students' ambition for a good spread plating technique.

