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Human-derived Biomaterials for Biomedical and Tissue Engineering Applications
Arun Kumar Singh1, Sonali Sundram1, Rishabha Malviya1
1Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India.
Current Pharmaceutical Design
|March 24, 2023
Summary
Innovative biomaterials, particularly those derived from the extracellular matrix (ECM), are crucial for advancing tissue engineering and regenerative medicine. These human-origin materials enhance cell function and tissue repair for biomedical applications.
Area of Science:
- Biomedical Engineering
- Regenerative Medicine
- Materials Science
Background:
- Biomaterials have a long history in wound healing and tissue restoration.
- Current clinical demands necessitate the development of novel biomaterials.
- Extracellular matrix (ECM) presents unique biological and biophysical properties for cell regulation.
Approach:
- This review summarizes recent trends in tissue engineering, including stem cells and 3D printing.
- Literature surveys were conducted across major scientific databases (PubMed, Scopus, Elsevier, Google Scholar).
- Focus is placed on human-origin biomaterials and their applications.
Key Points:
- Biomaterials are essential for tissue engineering to restore function in degenerated tissues/organs.
- Dynamic scaffolds mimicking natural tissue are being developed using biomaterials.
- Biomaterials significantly contribute to the success of biomedical devices.
Conclusions:
- Advances in understanding biomaterials and their role in tissue formation offer new prospects.
- Biomaterials derived from ECM provide a microenvironment that regulates cell functions.
- The integration of biomaterials is pivotal for the future of tissue engineering and regenerative medicine.

