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Disclosing Conflicts of Interest to Potential Research Participants: Good for Nothing?
1Professor of medical ethics in medicine in the Division of Medical Ethics at Weill Cornell Medicine.
Ethics & Human Research
|March 28, 2023
Summary
Financial conflict of interest (COI) disclosure to research participants is often ineffective. Current disclosure practices may not achieve ethical goals due to flawed implementation or inappropriate means.
Area of Science:
- Biomedical ethics
- Research integrity
- Science policy
Background:
- Commercialization of science raises concerns about financial conflicts of interest (COIs).
- COIs can compromise research integrity and participant welfare.
- Policies mandating COI disclosure to participants are widespread.
Purpose of the Study:
- To critically evaluate the ethical effectiveness of disclosing financial conflicts of interest to research participants.
- To determine if current disclosure practices achieve their intended moral objectives.
Main Methods:
- Philosophical analysis of COI disclosure policies.
- Ethical argumentation regarding the means and ends of disclosure.
Main Results:
- Disclosure may be an inappropriate means to achieve certain ethical goals.
- Even when disclosure could be appropriate, flawed implementation hinders its effectiveness.
- Current disclosure practices often fail to meet their moral aims.
Conclusions:
- Rethinking current COI disclosure policies is necessary.
- Alternative or improved strategies are needed to protect research participants and uphold research integrity.
- The ethical justification and practical implementation of COI disclosure require further scrutiny.
Keywords:
conflict of interestdisclosurehuman research ethicshuman subjects researchinformed decision-makingresearch participant welfaretrusttrustworthy scienceMore Related Videos
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