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Current global research on mandibular defect: A bibliometric analysis from 2001 to 2021
Yongdi Li1,2, Duchenhui Li1,2, Zhenglong Tang1,2
1School of Basic Sciences, Guizhou Medical University, Guiyang, China.
Frontiers in Bioengineering and Biotechnology
|April 10, 2023
Summary
Research on mandibular defects is increasing, with a focus on new surgical techniques. Future trends include computer-aided design, 3D printing, and bone tissue engineering for better reconstruction.
Area of Science:
- Oral and Maxillofacial Surgery
- Biomaterials Science
- Regenerative Medicine
Background:
- Mandibular defects arise from various causes, including trauma, tumors, and congenital issues, posing significant challenges to jaw function and repair.
- Existing treatments for mandibular defects often involve complex procedures with potential complications like skin flap issues and prolonged recovery.
- The intricate nature of the jaw necessitates advanced solutions for effective bone repair and functional restoration.
Purpose of the Study:
- To conduct a bibliometric analysis of research on mandibular defects from 2001 to 2021.
- To identify current research trends and predict future directions in the field of mandibular defect treatment.
- To provide an overview of the global research landscape concerning mandibular defects.
Main Methods:
- Bibliometric analysis of 4,377 articles published between 2001 and 2021.
- Data sourced from the Web of Science Core Collection.
- Visualization and analysis performed using VOSviewer, CiteSpace, and Scimago Graphica software.
Main Results:
- A significant increase in publications on mandibular defects over the past two decades, with the United States, China, and Germany as leading contributors.
- Key research areas identified include mandibular defects, reconstruction, and bone regeneration, with emerging focus on computer-aided design, 3D printing, and virtual surgical planning.
- Wikesjoe and Ulf Mai E were highly prolific authors, and Shanghai Jiaotong University led in institutional output.
Conclusions:
- The field of mandibular defect research is expanding, with a growing adoption of innovative surgical procedures.
- Current research frontiers emphasize advanced technologies like computer-aided design, 3D printing for surgical guides, and bone tissue engineering.
- These advancements aim to improve outcomes for patients with complex mandibular defects.

