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Related Experiment Video

Updated: Aug 3, 2025

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
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Marijuana Legalization in Colorado: Increasing Potency, Changing Risk Perceptions, and Emerging Public Health

Jesse D Hinckley1, Christian Hopfer1

  • 1Division of Addiction Science, Prevention, & Treatment, Department of Psychiatry, University of Colorado School of Medicine, Aurora, CO, 80045, USA.

Adolescent Psychiatry (Hilversum, Netherlands)
|April 10, 2023
PubMed
Summary
This summary is machine-generated.

Marijuana legalization in Colorado led to increased commercialization and higher potency product use among young adults. Emerging concerns include mental health issues and acute care visits, with limited evidence on long-term effects.

Keywords:
E-cigarette and vaping associated lung injury (EVALI)Marijuanaadolescentcannabiscannabis-induced psychosismarijuana legalizationyoung adultΔ-9-tetrahydrocannabinol

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Area of Science:

  • Public Health
  • Cannabis Research
  • Adolescent Health

Background:

  • Gradual marijuana legalization in Colorado occurred through political processes.
  • Commercialization followed legalization, increasing product availability and lowering costs.

Purpose of the Study:

  • To review the history of marijuana legalization in Colorado.
  • To describe shifts in product availability, use patterns, and risk perceptions.
  • To identify emerging concerns for adolescents and young adults.

Main Methods:

  • Literature review focusing on marijuana legalization.
  • Analysis of shifts in product availability, use patterns, and risk perceptions.
  • Examination of emerging concerns related to adolescent and young adult use.

Main Results:

  • Increased commercialization with more dispensaries and diverse products (edibles, concentrates).
  • Young adult marijuana use patterns show an increase, particularly with high-potency products.
  • Emerging concerns include acute care visits, mental health disorders, psychosis, impaired driving, lung injuries, and pregnancy use.

Conclusions:

  • Scientific evidence on the effects of high-potency marijuana products is limited.
  • Treatment considerations for youth marijuana use and psychiatric disorders are influenced by low risk perceptions.