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Updated: Aug 2, 2025

Measuring the Structure, Composition, and Change of Underwater Environments with Large-area Imaging
Published on: April 18, 2025
The Future of LAAC-In 5, 10, and 20 Years
Matthew J Daniels1, Adrian Parry-Jones2
1Manchester Heart Centre, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, UK; Division of Cardiovascular Sciences, Manchester Academic Health Sciences Centre, University of Manchester, UK; Division of Cell Matrix Biology and Regenerative Medicine, University of Manchester, Manchester, UK.
Abstract:
Early experience with percutaneous LAA closure documented complication rates of ∼10%, with failure to implant devices in ∼10% of patients. These numbers are unrecognizable in contemporary practice due to the iterative changes made largely in the last 10 years. Here we look forward to ask what might change, and when, to bring percutaneous LAA closure out of the niche early adopter centers into routine use. We consider the opportunity to incorporate different technologies into LAAc devices in the context of managing patient with atrial fibrillation. Finally, we consider how to make the procedure safer and more effective.
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