Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Conservative Site-specific Recombination and Phase Variation

Conservative Site-specific Recombination and Phase Variation

Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...

Synthetic Biology

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...

DNA Bacteriophages

DNA Bacteriophages

Bacteriophages, or phages, are viruses that specifically infect bacteria, utilizing their genetic material to hijack host cellular machinery for replication. DNA bacteriophages employ single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA) genomes. These phages exhibit diverse replication strategies and host interactions, influencing their ecological roles and applications in biotechnology and medicine.ssDNA BacteriophagesssDNA phages, with their small genomes, utilize unique strategies to...

DNA-only Transposons

DNA-only Transposons

DNA-only transposons are called autonomous transposons since they code for the enzyme transposase that is required for the transposition mechanism. Insertion of transposons can alter gene functions in multiple ways. They can mutate the gene, alter gene expression by introducing a novel promoter or insulator sequence, introduce new splice sites, and change the mRNA transcripts produced, or remodel chromatin structure.
The donor site from where the transposon is excised is either degraded or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mechanism for a molecular assembler of sequence-controlled polymers using parallel DNA and a DNA polymerase.

Nanoscale horizons·2025

Same author

A New Architecture for DNA-Templated Synthesis in Which Abasic Sites Protect Reactants from Degradation.

Angewandte Chemie (International ed. in English)·2024

Same author

Enhancing Neuronal Cell Uptake of Therapeutic Nucleic Acids with Tetrahedral DNA Nanostructures.

Small (Weinheim an der Bergstrasse, Germany)·2024

Same author

A modular RNA delivery system comprising spherical nucleic acids built on endosome-escaping polymeric nanoparticles.

Nanoscale advances·2023

Same author

A DNA molecular printer capable of programmable positioning and patterning in two dimensions.

Science robotics·2022

Same author

Strategies for Constructing and Operating DNA Origami Linear Actuators.

Small (Weinheim an der Bergstrasse, Germany)·2021

Same journal

DNA origami snaps into place.

Science robotics·2026

Same journal

A high-endurance DNA origami snap-through switch for functional nanoscale control.

Science robotics·2026

Same journal

Learning flight navigation like a honey bee.

Science robotics·2026

Same journal

Is your robot vacuum cleaner spying on you?

Science robotics·2026

Same journal

Do people feel safe in a robot's presence?

Science robotics·2026

Same journal

Stop chasing identical outcomes in HRI replication: Learn from the differences.

Science robotics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 1, 2025

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

Reconfigurable self-assembled DNA devices.

Erik Benson¹, Jonathan Bath^2,3

¹Science for Life Laboratory, Department of Gene Technology, KTH Royal Institute of Technology, Stockholm, Sweden.

Science Robotics

|April 26, 2023

Summary

This summary is machine-generated.

DNA origami enables modular and reconfigurable systems, paving the way for the creation of advanced molecular robots for various applications.

More Related Videos

Designing a Bio-responsive Robot from DNA Origami

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Published on: November 25, 2015

Related Experiment Videos

Last Updated: Aug 1, 2025

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

Designing a Bio-responsive Robot from DNA Origami

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Published on: November 25, 2015

Area of Science:

Biotechnology
Nanotechnology
Molecular Engineering

Background:

Traditional systems often lack adaptability.
The need for precise molecular machinery is growing.

Purpose of the Study:

To demonstrate the feasibility of DNA origami for creating modular and reconfigurable systems.
To explore the potential of these systems in generating molecular robots.

Main Methods:

Utilizing DNA origami techniques for structural self-assembly.
Designing DNA components for modularity and reconfigurability.

Main Results:

Successfully created modular systems using DNA origami.
Demonstrated the reconfigurable nature of these DNA-based structures.
Showcased the potential for generating functional molecular robots.

Conclusions:

DNA origami is a powerful platform for building adaptable molecular systems.
This approach holds significant promise for the future of molecular robotics.