Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

178
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
178

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perinatal Airway Risk for Individuals With Isolated Cleft Spectrum.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association·2025
Same author

A biomechanical comparative study of passive stomach tissue from pigs and humans.

Acta biomaterialia·2025
Same author

Implications of compressive loading of the stomach wall: Interplay between mechanical deformation and microstructure.

Acta biomaterialia·2024
Same author

AT1b receptors contribute to regional disparities in angiotensin II mediated aortic remodelling in mice.

Journal of the Royal Society, Interface·2024
Same author

Perinatal Airway Management Mandibular Anomalies: A National Inpatient Cohort Analysis.

The Laryngoscope·2024
Same author

Western diet-induced obesity results in brain mitochondrial dysfunction in female Ossabaw swine.

Frontiers in molecular neuroscience·2024
Same journal

Structural imbalances in EPA Perceptions: A multi-center study of cognitive differences between faculty and trainees in Chinese surgical residency training.

Surgery open science·2026
Same journal

Newly identified parathormone-secreting cells in the thyroid tissue.

Surgery open science·2026
Same journal

A qualitative human factors investigation of the impact of intraoperative CT-based navigation on interprofessional work in the operating theatre.

Surgery open science·2026
Same journal

Perioperative outcomes of robotic-assisted liver surgery: A comparison between patients with and without previous abdominal surgery.

Surgery open science·2026
Same journal

A qualitative interview study of acute care surgeons' approach to literature acquisition: Are you up to date on staying up to date?

Surgery open science·2026
Same journal

Timing of a laparoscopic cholecystectomy in acute moderately severe to severe biliary pancreatitis.

Surgery open science·2026
See all related articles

Related Experiment Video

Updated: Jul 31, 2025

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage
07:51

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage

Published on: November 4, 2010

22.0K

Mechanobiological considerations in colorectal stapling: Implications for technology development.

Alexander W Caulk1, Monideepa Chatterjee1, Samantha J Barr1

  • 1Surgical Innovations, Medtronic, North Haven, CT, USA.

Surgery Open Science
|May 9, 2023
PubMed
Summary
This summary is machine-generated.

Surgical stapling improves outcomes, but anastomotic leaks persist. Understanding tissue mechanics and cell mechanosensing is crucial for preventing these adverse events in gastrointestinal surgery.

Keywords:
AnastomosisColorectumMechanotransductionSurgical staplingTissue mechanicsWound healing

More Related Videos

Performing Colonoscopic-Guided Pinch Biopsies in Mice and Evaluating Subsequent Tissue Changes
08:52

Performing Colonoscopic-Guided Pinch Biopsies in Mice and Evaluating Subsequent Tissue Changes

Published on: February 5, 2021

4.5K
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

577

Related Experiment Videos

Last Updated: Jul 31, 2025

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage
07:51

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage

Published on: November 4, 2010

22.0K
Performing Colonoscopic-Guided Pinch Biopsies in Mice and Evaluating Subsequent Tissue Changes
08:52

Performing Colonoscopic-Guided Pinch Biopsies in Mice and Evaluating Subsequent Tissue Changes

Published on: February 5, 2021

4.5K
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

577

Area of Science:

  • Biomedical Engineering
  • Gastrointestinal Surgery
  • Wound Healing Research

Background:

  • Minimally invasive surgery (MIS) and surgical stapling enhance patient outcomes.
  • Anastomotic leaks remain a significant challenge, particularly in colorectal procedures.
  • Tissue mechanosensing's role in gastrointestinal wound healing is poorly understood.

Purpose of the Study:

  • To review the current understanding of tissue mechanics in surgical intervention.
  • To explore the mechanobiological responses of tissue to surgical forces.
  • To identify opportunities for innovation in MIS to improve patient outcomes.

Main Methods:

  • Literature review of surgical stapling advancements.
  • Analysis of factors contributing to anastomotic leaks.
  • Examination of cellular mechanosensing in wound healing.

Main Results:

  • Surgical stapling offers ease and efficacy but does not eliminate anastomotic leaks.
  • Tissue mechanical changes during and after surgery are complex.
  • Mechanosensing is critical in disease but understudied in GI wound healing.

Conclusions:

  • Further research into intraoperative tissue mechanics and postoperative mechanobiology is essential.
  • Understanding these mechanical factors can lead to innovations in MIS.
  • Improving patient outcomes by mitigating anastomotic leaks is a key goal.