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Updated: Jul 30, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Tongue necrosis secondary to giant cell arteritis
Juan Cantón De Seoane1, Luis Alberto Gutiérrez Guédez2, Ana Belén Rodríguez Cambrón3
1Internal Medicine, Hospital Universitario de Toledo, Toledo, Spain cantonseoane@gmail.com.
Abstract:
Tongue necrosis is a rare clinical finding because of its rich vascularisation. Giant cell arteritis (GCA) is the most frequent cause of it, and when present, it is usually one side affected. We describe a patient with several months of constitutional syndrome; during that period, she develops headache followed by tongue necrosis, which lead to clinical suspicion of GCA, later confirmed by a temporal artery biopsy. Before the biopsy, she was treated with corticosteroids. We discuss this illness and tongue necrosis as a rare manifestation to consider.
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