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Updated: Jul 27, 2025

A Contusion Model of Severe Spinal Cord Injury in Rats
Published on: August 17, 2013
Refractory compartment syndrome after antivenom administration for an Eastern Diamondback Rattlesnake bite requiring
Daniel R Cavazos1,2, Rebecca Schultz2, Devan O Higginbotham1,2
1Detroit Medical Center, Detroit, MI, USA.
Case:
56-year-old male who developed post-snakebite compartment syndrome (PSCS) of the upper extremity which was refractory to antivenom administration. He had elevated compartment pressure measurements in his upper extremity. He underwent open fasciotomy for the compartment syndrome, followed by delayed primary closure and skin grafting. He now has two years of follow-up with a functional upper extremity.
Conclusion:
This is a case of a patient who suffered post-snakebite compartment syndrome from his pet Eastern Diamondback Rattlesnake. This case highlights the importance of correctly diagnosing compartment syndrome and validates fasciotomy as a treatment measure for confirmed post-snakebite compartment syndrome (PSCS).

