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A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
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Surviving Pulmonary Tuberculosis: Navigating the Long Term Respiratory Effects
Arpit Bansal1, Vishnu R Yanamaladoddi2, Sai Suseel Sarvepalli1
1Internal Medicine, Narayana Medical College, Nellore, IND.
Cureus
|June 12, 2023
Summary
Tuberculosis (Mycobacterium tuberculosis) can cause lasting lung damage, even after treatment. This review highlights the link between tuberculosis and chronic respiratory disorders, emphasizing prevention.
Area of Science:
- Pulmonology
- Infectious Diseases
- Public Health
Background:
- Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a major global health concern.
- Risk factors for TB include developing country residence, poor ventilation, smoking, and male sex.
- TB infection can independently impair pulmonary function.
Purpose of the Study:
- To review existing studies on how TB impairs lung function.
- To explore the long-term pulmonary consequences of TB.
- To investigate the relationship between treated TB and chronic lung disorders.
Main Methods:
- Systematic review of multiple studies on tuberculosis and lung function.
- Analysis of tuberculosis's impact on pulmonary function post-treatment.
- Examination of the association between tuberculosis and obstructive/restrictive lung disorders.
Main Results:
- Tuberculosis significantly impacts lung function, with lasting effects even after treatment.
- A notable correlation exists between chronic respiratory diseases and a history of tuberculosis.
- Tuberculosis is linked to both obstructive and restrictive lung disorders.
Conclusions:
- Tuberculosis can lead to persistent lung function impairment.
- The link between treated TB and chronic respiratory conditions is significant.
- Preventing tuberculosis is more effective than treating its long-term lung consequences.
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