FUNCTIONAL CHARACTERISTICS OF THE CARDIOVASCULAR SYSTEM OF PATIENTS WITH ISCHEMIC HEART DISEASE WITH OBESITY

Area of Science:

• Cardiology
• Internal Medicine
• Obesity Research

Background:

• Coronary heart disease (CHD) and obesity are significant global health concerns.
• The interplay between CHD and obesity can lead to complex cardiovascular complications.
• Understanding the functional characteristics of the cardiovascular system in patients with both conditions is crucial.

Purpose of the Study:

• To investigate the specific functional characteristics of the cardiovascular system in patients diagnosed with both coronary heart disease and obesity.
• To identify potential biomarkers for early detection of cardiovascular issues in this patient cohort.

Main Methods:

• A study involving 130 participants, including 65 patients with CHD and obesity and 45 healthy controls.
• Cardiovascular parameters such as blood pressure, end-diastolic volume, end-systolic volume, end-diastolic size, and end-systolic size were measured.
• Statistical analysis was performed to compare the groups.

Main Results:

• Patients with CHD and obesity demonstrated significantly higher systolic and diastolic blood pressure compared to healthy controls.
• Elevated end-diastolic and end-systolic volumes and sizes were observed in the CHD and obesity group.
• All measured cardiovascular parameters showed statistically significant differences between the patient and control groups (p<0.001).

Conclusions:

• The study identified distinct functional cardiovascular disorders in patients with comorbid CHD and obesity.
• These findings can facilitate the early diagnosis of cardiovascular complications in patients with CHD and obesity.
• The results support the development of targeted therapeutic strategies for this patient population.